GuideIn Medical

Non-invasive Guided Endotracheal Intubation Device

About us

Guide In Medical is a medical device company specializing in the respiratory field. Established in 2015 in Nazareth, Israel, the company has developed a novel groundbreaking non-invasive guided intubation device. Our device enables clear identification of the trachea, as well as fast, accurate and safe intubations even in the most difficult clinical scenarios in which visualization of the trachea is very limited.

The company is ISO 13485 certified and received the CE Mark while FDA market approval is expected during 2017. Guide In has secured funding from NGT3VC and CTS group, the latter being one of the most prominent healthcare companies in Israel.


The Need

Endotracheal intubation is the placement of an endotracheal tube (ETT) into the trachea of patients who need artificial ventilation to maintain a constant supply of oxygen to the lungs.

The core challenge in endotracheal intubation is having the ability to correctly and precisely identify and visualize the location of the vocal cords, which mark the point of entry to the trachea, and to avoid misplacement of the ETT within the esophagus.

In cases in which visualization is limited or otherwise impaired due to anatomical malformations, secretions, blood, obesity or lack of expertise of the attending medical staff, the chances of such misplacement rise dramatically and can lead to severe clinical complications.

Tracheal injuries due to imprecise intubation are associated with a hospital stay prolonged by 1.1 days, on average, and an added cost of $1,888 per case. Readmission due to tracheal injury can last as long as 4.7 days on average, resulting in an average cost of $11,025.

The Product

Guide In Medical's guided intubation device is based on an electronic illumination patch, which is placed on the patient’s neck.

Once activated, the device transmits light of a specific wavelength to the underlying tissues. The light is completely absorbed by the surrounding tissues, while a fraction of it is emitted solely by the trachea, thus enabling the clear identification of its position.

Video laryngoscopes, which are capable of detecting the emitted light, are used to guide the insertion of the ETT into the trachea.

The Guide In device is disposable and is uniquely capable of transforming ordinary video intubation devices into guided devices, thus facilitating intubation even in the most difficult clinical scenarios.


The Market

Approximately 50 million intubation procedures are performed globally each year.
The US is the largest market, accounting for roughly one third of these procedures.
The global anesthesia video laryngoscope market, which generated $170.6 million in 2015 and will likely reach $329.3 million by 2020, is constantly growing, at a CAGR of 14.06%.

Management Team:

Ariel Shrem, Co-Founder & CEO

Ariel has vast experience in emergency medicine as a graduate of the Israeli Air Force (IAF) elite airborne rescue and evacuation unit (Unit 669). He brings managerial experience and project management skills in the medical-device and pharmaceutical industries.

Ariel holds a B.Sc. in Biology and an MBA (with distinction) specializing in marketing management and strategy & entrepreneurship, both degrees from the Hebrew University, Jerusalem.

Yossi Shalev, CTO

Yossi Shalev brings 16 years of R&D, mechanical design, project management and team leadership experience in the medical-device and electro-optics industries. Yossi holds a B.Sc. from Ben-Gurion University in the Negev, and an M.Sc. in mechanical engineering from Tel Aviv University. Prior to joining Guide-In, Yossi served as a mechanical team-leader in Medingo which developed the smallest innovative Insulin-pump and was acquired by Roche in 2010. He also served as the R&D mechanics leader of Pebbles-Interfaces, which developed an innovative 3D-Gesture Sensor and was acquired by Facebook in 2015.

Nizar Mishael, CFO

Nizar has hands-on financial management experience at all levels: from seed investment through early and late financial rounds. He served as managing partner and CFO of NGT3vc early stage fund. Nizar is a certified CPA and holds an MBA from Tel Aviv University’s Recanati program.

Elchanan Fried MD, Co-Founder & Medical Advisor

Dr. Fried is the head of the ICU at Hadassah Medical Center, Mt. Scopus, Jerusalem. He had his residency and a fellowship in Hadassah's medical centers, and a critical care fellowship in Toronto, Canada. He was an instructor and physician in the medical corps of the Israel Defense Forces (IDF). Elchanan has great knowledge, skill and expertise in emergency medicine.

Contact information

Ariel Shrem ,B.SC, MBA
CEO&Co-Founder , NGT3 VC Technological Incubator

P.O. Box 1252, Nazareth Illit 17111, Israel
Cellular: +972-58-762-2811
Work:     +972-4-6098606
Fax:        +972-4-6564129
Email:     ariel@guideinmed.com

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